Set against the backdrop of 1950s New York, âMotherless Brooklynâ follows Lionel Essrog (Norton), a lonely private detective afflicted with Touretteâs Syndrome, as he ventures to solve his friendâs murder. Armed only with a few clues and the powerful engine of his obsessive mind, Lionel unravels closely-guarded secrets that hold the fate of the whole city in the balance.